Invention Grant
US09254288B2 Susceptibility of tumors to tyrosine kinase inhibitors and treatment thereof
有权
肿瘤对酪氨酸激酶抑制剂的敏感性及其治疗
- Patent Title: Susceptibility of tumors to tyrosine kinase inhibitors and treatment thereof
- Patent Title (中): 肿瘤对酪氨酸激酶抑制剂的敏感性及其治疗
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Application No.: US13889337Application Date: 2013-05-07
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Publication No.: US09254288B2Publication Date: 2016-02-09
- Inventor: Pamela Michelle Pollock
- Applicant: Pamela Michelle Pollock
- Applicant Address: US AZ Phoenix AU Queensland
- Assignee: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE,QUEENSLAND UNIVERSITY OF TECHNOLOGY
- Current Assignee: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE,QUEENSLAND UNIVERSITY OF TECHNOLOGY
- Current Assignee Address: US AZ Phoenix AU Queensland
- Main IPC: A61K31/495
- IPC: A61K31/495 ; A61K31/506 ; A61K31/5025 ; A61K31/496 ; A61K31/4709 ; C12Q1/68 ; A61K31/497 ; A61K31/51
Abstract:
This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly FGFR2 variants, which are linked to drug resistance. The disclosure further provides methods of diagnosis and theranosis, using these molecules and fragments thereof, and kits for employing these methods and compositions.
Public/Granted literature
- US20130296326A1 SUSCEPTIBILITY OF TUMORS TO TYROSINE KINASE INHIBITORS AND TREATMENT THEREOF Public/Granted day:2013-11-07
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