Invention Grant
- Patent Title: Compositions comprising E-selectin antagonists and uses therefor
- Patent Title (中): 包含E-选择素拮抗剂的组合物及其用途
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Application No.: US12747324Application Date: 2008-12-09
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Publication No.: US09254322B2Publication Date: 2016-02-09
- Inventor: Jean-Pierre Levesque , Ingrid Winkler
- Applicant: Jean-Pierre Levesque , Ingrid Winkler
- Applicant Address: AU St. Lucia
- Assignee: The University of Queensland
- Current Assignee: The University of Queensland
- Current Assignee Address: AU St. Lucia
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- International Application: PCT/AU2008/001810 WO 20081209
- International Announcement: WO2009/073916 WO 20090618
- Main IPC: A61K38/08
- IPC: A61K38/08 ; A61K38/10 ; A61K38/18 ; A61K39/395 ; A61K45/06 ; A61K31/00 ; A61K31/7004 ; A61K31/7016 ; A61K31/702 ; A61K31/7032 ; A61K31/7056 ; A61K38/19 ; C07K7/06 ; C07K7/08 ; C07K16/28 ; C07K14/475 ; C07K14/54 ; C07K14/705 ; C07K7/00 ; A61K38/04 ; A61K38/17 ; A61K39/00
Abstract:
This invention discloses the use of an E-selectin antagonist and a mobilizer of hematopoietic stem cells or progenitor cells in methods and compositions for treating or preventing immunocompromised conditions resulting from medical treatment. The present invention is particular relevant for prophylaxis and/or treatment of hematopoeitic disorders including neutropenia, agranulocytosis, anemia and thrombocytopenia in individuals receiving or proposed to receive treatments that target rapidly dividing cells or that disrupt the cell cycle or cell division.
Public/Granted literature
- US20110020270A1 TREATMENT AND PROPHYLAXIS Public/Granted day:2011-01-27
Information query
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