Invention Grant
- Patent Title: Stable aqueous formulations of adenovirus vectors
- Patent Title (中): 稳定的腺病毒载体的水性制剂
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Application No.: US14208919Application Date: 2014-03-13
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Publication No.: US09254332B2Publication Date: 2016-02-09
- Inventor: Jan Jezek , Angela Buckler
- Applicant: Arecor Limited
- Applicant Address: GB Cambridge
- Assignee: Arecor Limited
- Current Assignee: Arecor Limited
- Current Assignee Address: GB Cambridge
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K47/38
- IPC: A61K47/38 ; A61K39/00 ; C12N15/86 ; A61K47/36 ; C12N7/00 ; C07K14/005 ; A61K9/00 ; A61K39/235 ; A61K48/00
Abstract:
The present invention is based on the surprising discovery that the inclusion of an anionic polymer in the adenovirus formulation enhances long-term stability of the vector composition. An aqueous formulation comprising an adenovirus vector and at least one anionic polymer is provided, together with methods of the preparation of a storage stable adenovirus aqueous formulation.
Public/Granted literature
- US20140348876A1 Stable Aqueous Formulations of Adenovirus Vectors Public/Granted day:2014-11-27
Information query
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