Invention Grant
- Patent Title: Quinazolinedione derivatives as PARP inhibitors
- Patent Title (中): 喹唑啉二酮衍生物作为PARP抑制剂
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Application No.: US14098720Application Date: 2013-12-06
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Publication No.: US09255080B2Publication Date: 2016-02-09
- Inventor: Ludo Edmond Josephine Kennis , Josephus Carolus Mertens , Jacobus Alphonsus Josephus Van Dun , Maria Victorina Francisca Somers , Walter Boudewijn Leopold Wouters
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Priority: EP04076885 20040630
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/06 ; C07D401/14 ; C07D403/12 ; C07D405/14 ; A61K31/517 ; A61K45/06
Abstract:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, L1, L2, X, Y and Z have defined meanings.
Public/Granted literature
- US20140100239A1 QUINAZOLINEDIONE DERIVATIVES AS PARP INHIBITORS Public/Granted day:2014-04-10
Information query
