Invention Grant
- Patent Title: Heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators
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Application No.: US14367823Application Date: 2012-12-20
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Publication No.: US09255090B2Publication Date: 2016-02-09
- Inventor: Hamed Aissaoui , Christoph Boss , Sylvia Richard-Bildstein , Romain Siegrist
- Applicant: Actelion Pharmaceuticals Ltd.
- Applicant Address: CH Allschwil
- Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee Address: CH Allschwil
- Agency: Arent Fox LLP
- Priority: WOPCT/IB2012/057541 20121220
- International Application: PCT/IB2012/057541 WO 20121220
- International Announcement: WO2013/093842 WO 20130627
- Main IPC: C07D209/44
- IPC: C07D209/44 ; C07D217/06 ; C07D223/06 ; C07D223/16 ; C07D401/06 ; C07D405/06 ; C07D413/06 ; C07D417/06 ; A61K31/47 ; C07D401/12

Abstract:
The present invention relates to phenyl-substituted heterocyclyl derivatives of the formula (I), wherein Z, n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.
Public/Granted literature
- US20150252036A1 Heterocyclyl Derivatives and their use as Prostaglandin D2 Receptor Modulators Public/Granted day:2015-09-10
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