Invention Grant
- Patent Title: Polycyclic HERG activators
- Patent Title (中): 多环HERG激活剂
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Application No.: US14688397Application Date: 2015-04-16
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Publication No.: US09255093B2Publication Date: 2016-02-09
- Inventor: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
- Applicant: Gregory Raymond Bebernitz , Emma Cody , Tajesh Patel , Ming Qian , Lewis Whitehead , Thomas Zabawa , Frederic Zecri
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Joshua Roth
- Main IPC: C07D405/04
- IPC: C07D405/04 ; A61K31/41 ; C07D417/12 ; C07D405/14 ; C07D307/85 ; A61K31/343 ; C07D407/12 ; A61K31/357 ; A61K31/443 ; A61K31/428

Abstract:
The present invention provides a compound of formula I, in which R1, R2, X and R3 are defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20150299181A1 POLYCYCLIC HERG ACTIVATORS Public/Granted day:2015-10-22
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