Invention Grant
US09255099B2 Pyrazolo[3,4-D]pyrimidine-4,6(5H,7H)-diones as phosphodiesterase 1 inhibitors
有权
吡唑并[3,4-D]嘧啶-4,6(5H,7H) - 二磷酸二酯酶抑制剂
- Patent Title: Pyrazolo[3,4-D]pyrimidine-4,6(5H,7H)-diones as phosphodiesterase 1 inhibitors
- Patent Title (中): 吡唑并[3,4-D]嘧啶-4,6(5H,7H) - 二磷酸二酯酶抑制剂
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Application No.: US12303618Application Date: 2007-06-06
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Publication No.: US09255099B2Publication Date: 2016-02-09
- Inventor: Peng Li , Lawrence P. Wennogle
- Applicant: Peng Li , Lawrence P. Wennogle
- Applicant Address: US NY New York
- Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee: INTRA-CELLULAR THERAPIES, INC.
- Current Assignee Address: US NY New York
- Agency: Hoxie & Associates LLC
- International Application: PCT/US2007/070551 WO 20070606
- International Announcement: WO2007/143705 WO 20071213
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P11/06 ; A61P13/08 ; A61P15/00 ; A61P19/10 ; A61P25/16 ; A61P25/18 ; A61P25/22 ; A61P25/28 ; A61P25/30 ; A61P37/00 ; A61P37/08 ; A61P9/10
![Pyrazolo[3,4-D]pyrimidine-4,6(5H,7H)-diones as phosphodiesterase 1 inhibitors](/abs-image/US/2016/02/09/US09255099B2/abs.jpg.150x150.jpg)
Abstract:
2-(optionally hetero)arylmethyl-3-(optionally hetero)arylamino-[2H]-pyrazolo[3,4-d]pyrimidine-4,6(5H, 7H)-diones, for example, a compound of Formula I: in free, salt or prodrug form, are useful as pharmaceuticals, particularly as phosphodiesterase 1 inhibitors.
Public/Granted literature
- US20100173878A1 ORGANIC COMPOUNDS Public/Granted day:2010-07-08
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