Invention Grant
![Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators](/docs/US/2016-02-09/US09255110B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators
- Patent Title (中): 吡唑并[1,5a]嘧啶衍生物，为IRAK4调节剂
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Application No.: US14243074Application Date: 2014-04-02
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Publication No.: US09255110B2Publication Date: 2016-02-09
- Inventor: Nidhi Arora , Shaoqing Chen , Johannes Cornelius Hermann , Andreas Kuglstatter , Sharada Shenvi Labadie , Clara Jeou Jen Lin , Matthew C. Lucas , Amy Geraldine Moore , Eva Papp , Francisco Xavier Talamas , Jutta Wanner , Yansheng Zhai
- Applicant: Hoffmann-La Roche Inc. , Roche Palo Alto LLC
- Applicant Address: US CA Palo Alto US NJ Notley
- Assignee: ROCHE PALO ALTO LLC,HOFFMANN-LA ROCHE INC.
- Current Assignee: ROCHE PALO ALTO LLC,HOFFMANN-LA ROCHE INC.
- Current Assignee Address: US CA Palo Alto US NJ Notley
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D487/04
![Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators](/abs-image/US/2016/02/09/US09255110B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.
Public/Granted literature
- US20140303149A1 PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS Public/Granted day:2014-10-09
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