Invention Grant
- Patent Title: Chimeric alphavirus replicon particles
- Patent Title (中): 嵌合甲病毒复制子颗粒
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Application No.: US12538432Application Date: 2009-08-10
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Publication No.: US09255126B2Publication Date: 2016-02-09
- Inventor: John M. Polo , Silvia Perri , Kent Thudium , Zequn Tang
- Applicant: John M. Polo , Silvia Perri , Kent Thudium , Zequn Tang
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agent Laurence Shumway; Helen Lee
- Main IPC: A61K39/193
- IPC: A61K39/193 ; A61K39/12 ; C12N7/01 ; C12N15/86 ; C12N15/40 ; C07K14/005 ; C12N7/00 ; A61K39/00
Abstract:
Chimeric alphavirus particles and alphavirus replicon RNAs are provided including methods of making and using same. The alphavirus replicon RNAs comprise deletions in one or more nonstructural proteins. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle are disclosed.
Public/Granted literature
- US20090304745A1 CHIMERIC ALPHAVIRUS REPLICON PARTICLES Public/Granted day:2009-12-10
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