Invention Grant
- Patent Title: Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system
- Patent Title (中): 卡他莫拉菌与上皮细胞,细胞外基质蛋白和补体系的相互作用
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Application No.: US14508033Application Date: 2014-10-07
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Publication No.: US09255127B2Publication Date: 2016-02-09
- Inventor: Arne Forsgren , Kristian Riesbeck
- Applicant: Olle Forsgren , Kristian Riesbeck
- Applicant Address: SE Falsterbo
- Assignee: Arne Forsgren AB
- Current Assignee: Arne Forsgren AB
- Current Assignee Address: SE Falsterbo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Main IPC: A61K39/104
- IPC: A61K39/104 ; C07K14/21

Abstract:
The present disclosure relates to surface proteins of Moraxella catarrhalis and their ability to interact with epithelial cells via cell-associated fibronectin and laminin, and also to their ability to inhibit the complement system. These surface proteins are useful in the preparation of vaccines. The present disclosure also provides peptides interacting with fibronectin, laminin and the complement system.
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