Invention Grant
US09255133B2 Alteration of cell membrane for new functions using IL-2 and streptavidin
有权
使用IL-2和链霉抗生物素蛋白改变新功能的细胞膜
- Patent Title: Alteration of cell membrane for new functions using IL-2 and streptavidin
- Patent Title (中): 使用IL-2和链霉抗生物素蛋白改变新功能的细胞膜
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Application No.: US14280940Application Date: 2014-05-19
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Publication No.: US09255133B2Publication Date: 2016-02-09
- Inventor: Haval Shirwan
- Applicant: University of Louisville Research Foundation, Inc.
- Applicant Address: US KY Louisville
- Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
- Current Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
- Current Assignee Address: US KY Louisville
- Agency: Foley & Lardner LLP
- Main IPC: A61K38/20
- IPC: A61K38/20 ; C07K14/55 ; A61P31/00 ; A61P35/00 ; A61K39/00 ; A61K47/48 ; B82Y5/00 ; C07K14/705 ; C12N5/00 ; C07K14/36 ; C07K14/46 ; C07K14/525 ; A61K38/00 ; A61K35/12
Abstract:
Methods and compositions are provided for the persistent modification of cell membranes with exogenous proteins so as to alter the function of the cell to achieve effects similar to those of gene therapy, without the introduction of exogenous DNA. DNA sequences, the proteins and polypeptides embodying these sequences are disclosed for modulating the immune system. The modulations include down-regulation, up-regulation and apoptosis.
Public/Granted literature
- US20150086506A1 ALTERATION OF CELL MEMBRANE FOR NEW FUNCTIONS Public/Granted day:2015-03-26
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