Invention Grant
US09255137B2 Methods of promoting fat loss comprising administering an ALK7 inhibitor
有权
促进脂肪减少的方法包括施用ALK7抑制剂
- Patent Title: Methods of promoting fat loss comprising administering an ALK7 inhibitor
- Patent Title (中): 促进脂肪减少的方法包括施用ALK7抑制剂
-
Application No.: US14163599Application Date: 2014-01-24
-
Publication No.: US09255137B2Publication Date: 2016-02-09
- Inventor: John Knopf , Jasbir Seehra
- Applicant: Acceleron Pharma Inc.
- Applicant Address: US MA Cambridge
- Assignee: Acceleron Pharma Inc.
- Current Assignee: Acceleron Pharma Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K14/71 ; A61K31/663 ; A61K9/00 ; A61K9/12 ; A61K38/00
Abstract:
The invention relates to ALK7 soluble receptors and their uses as antagonists of the function of certain ligands such as GDF-8 (Myostatin) and GDF-11. The ALK7 soluble receptor of the invention is useful as antagonists of GDF-8 and GDF-11 in the treatment of neuronal diseases or conditions such as stroke, spinal cord injury, and all peripheral nerve diseases. The ALK7 soluble receptor of the invention is also useful as GH (growth hormone) equivalent, and for increasing muscle mass.
Public/Granted literature
- US20140205600A1 METHODS OF PROMOTING FAT LOSS COMPRISING ADMINISTERING AN ALK7 INHIBITOR Public/Granted day:2014-07-24
Information query
