Invention Grant
US09255257B2 PmST1 mutants for chemoenzymatic synthesis of sialyl lewis X compounds
有权
PmST1突变体用于唾液酸路易斯X化合物的化学酶合成
- Patent Title: PmST1 mutants for chemoenzymatic synthesis of sialyl lewis X compounds
- Patent Title (中): PmST1突变体用于唾液酸路易斯X化合物的化学酶合成
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Application No.: US14237334Application Date: 2012-08-06
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Publication No.: US09255257B2Publication Date: 2016-02-09
- Inventor: Xi Chen , Go Sugiarto , Kam Lau
- Applicant: Xi Chen , Go Sugiarto , Kam Lau
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Kilpatrick Townsend and Stockton LLP
- International Application: PCT/US2012/049748 WO 20120806
- International Announcement: WO2013/022836 WO 20130214
- Main IPC: C12P19/18
- IPC: C12P19/18 ; C12N9/10
Abstract:
The present invention provides mutants of PmST1 for the preparation of sialyl-Lewisx oligosaccharides, and other sialosides with decreased sialidase activity.
Public/Granted literature
- US20140302565A1 PMST1 MUTANTS FOR CHEMOENZYMATIC SYNTHESIS OF SIALYL LEWIS X COMPOUNDS Public/Granted day:2014-10-09
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