Invention Grant
- Patent Title: Compositions and methods for treating tumors, fibrosis, and pulmonary alveolar proteinosis
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Application No.: US14332001Application Date: 2014-07-15
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Publication No.: US09255271B2Publication Date: 2016-02-09
- Inventor: Gera Neufeld
- Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
- Applicant Address: IL Haifa
- Assignee: Technion Research & Development Foundation Ltd
- Current Assignee: Technion Research & Development Foundation Ltd
- Current Assignee Address: IL Haifa
- Priority: IL184627 20070715
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12Q1/68 ; G01N33/573

Abstract:
The present disclosure provides pharmaceutical compositions and methods useful for modulating angiogenesis and for inhibiting metastasis, tumors, pulmonary alveolar proteinosis, and fibrosis in a mammalian tissue. Pharmaceutical compositions and methods include inhibitors of LOXL2 expression and activity, such as shRNA targeting LOXL2.
Public/Granted literature
- US20150044199A1 COMPOSITIONS AND METHODS FOR TREATING TUMORS, FIBROSIS, AND PULMONARY ALVEOLAR PROTEINOSIS Public/Granted day:2015-02-12
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