A high pressure proton exchange membrane based water electrolyzer system that may include a series of proton exchange membrane (PEM) cells that may be electrically coupled together and coupled to a proton exchange membrane to form a membrane electrode assembly (MEA) that is spiral wound onto a conductive center post, wherein an innermost PEM cell of the MEA may be electrically connected with the conductive center post, or center electrode, and wherein an outermost PEM cell of the MEA may be electrically coupled to pressure vessel cylinder, or outer electrode. Each PEM cell may include an anode portion and a cathode portion separated by a portion of the PEM membrane. In addition, a non-permeable separator layer may also be spiral wound around the conductive center post and separates the wound portions of the PEM core.