Invention Grant
US09255931B2 Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
有权
用于治疗和检测内皮素-1相关肾脏疾病的方法和组合物
- Patent Title: Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
- Patent Title (中): 用于治疗和检测内皮素-1相关肾脏疾病的方法和组合物
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Application No.: US13162010Application Date: 2011-06-16
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Publication No.: US09255931B2Publication Date: 2016-02-09
- Inventor: Gale Newman , Barbara A. Jacob-Mungin , Chamberlain Obialo
- Applicant: Gale Newman , Barbara A. Jacob-Mungin , Chamberlain Obialo
- Applicant Address: US GA Atlanta
- Assignee: MOREHOUSE SCHOOL OF MEDICINE
- Current Assignee: MOREHOUSE SCHOOL OF MEDICINE
- Current Assignee Address: US GA Atlanta
- Agency: Andrews Kurth LLP
- Agent Ping Wang
- Main IPC: A61K9/19
- IPC: A61K9/19 ; G01N33/68 ; A61K9/00 ; A61K31/40 ; A61K31/422 ; A61K31/505 ; A61K31/506 ; C12Q1/68 ; G01N33/569 ; G01N33/78
Abstract:
The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
Public/Granted literature
- US20110319333A1 METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES Public/Granted day:2011-12-29
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