A method for accelerating execution of read operations in a distributed interconnect peripheral bus is provided. The method comprises generating a first number of speculative read requests addressed to an address space related to a last read request served on the bus; sending the speculative read requests to a root component connected to the bus; receiving a second number of read completion messages from the root component of the bus; and sending a read completion message out of the received read completion messages component to the endpoint component only if the read completion message is respective of a real read request or a valid speculative read request out of the speculative read requests, wherein a real read request is issued by the endpoint component.