Invention Grant
- Patent Title: Polymeric artificial tear system
- Patent Title (中): 聚合人工泪液系统
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Application No.: US14180396Application Date: 2014-02-14
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Publication No.: US09259472B2Publication Date: 2016-02-16
- Inventor: Howard Allen Ketelson , David L. Meadows , James W. Davis
- Applicant: Alcon Research, Ltd.
- Applicant Address: US TX Fort Worth
- Assignee: Alcon Research, Ltd.
- Current Assignee: Alcon Research, Ltd.
- Current Assignee Address: US TX Fort Worth
- Main IPC: A61K47/26
- IPC: A61K47/26 ; A61K31/736 ; A61K9/00 ; A61K47/02 ; A61K47/10 ; A61K47/36 ; A61K31/08
Abstract:
The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.
Public/Granted literature
- US20140161760A1 POLYMERIC ARTIFICIAL TEAR SYSTEM Public/Granted day:2014-06-12
Information query
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