Invention Grant
US09260401B2 Method for preparing cabazitaxel from 10-deacetylbaccatin III in high yield, and novel intermediate therefor
有权
从10-脱乙酰浆果赤霉素III高收率制备卡巴他赛的方法及其新型中间体
- Patent Title: Method for preparing cabazitaxel from 10-deacetylbaccatin III in high yield, and novel intermediate therefor
- Patent Title (中): 从10-脱乙酰浆果赤霉素III高收率制备卡巴他赛的方法及其新型中间体
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Application No.: US14647147Application Date: 2013-12-03
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Publication No.: US09260401B2Publication Date: 2016-02-16
- Inventor: Na Young Lee , Seong Ho Kim , Young Min Kim , Jin Suk Cho , Moon Suk Kim
- Applicant: SAMYANG BIOPHARMACEUTICALS CORPORATION
- Applicant Address: KR Seoul
- Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
- Current Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
- Current Assignee Address: KR Seoul
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: KR10-2012-0139485 20121204
- International Application: PCT/KR2013/011084 WO 20131203
- International Announcement: WO2014/088281 WO 20140612
- Main IPC: C07D305/14
- IPC: C07D305/14 ; A61K31/337 ; C07D413/12 ; C07F7/18
Abstract:
The present invention relates to a novel method for preparing cabazitaxel from 10-deacetylbaccatin III, and a novel intermediate therefor, and more specifically, to: a method which allows cabazitaxel to be more easily prepared in a high yield and in a high purity within a short time compared with a conventional method by preparing cabazitaxel via a novel intermediate using 10-deacetylbaccatin III as a starting material, and thus is suitable for industrial mass production; and a novel intermediate therefor.
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