Invention Grant
US09260426B2 Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
有权
取代的1H-吡咯并[2,3-b]吡啶和1H-吡唑并[3,4-b]吡啶衍生物作为盐诱导型激酶2（SIK2）抑制剂
![Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors](/docs/US/2016-02-16/US09260426B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
- Patent Title (中): 取代的1H-吡咯并[2,3-b]吡啶和1H-吡唑并[3,4-b]吡啶衍生物作为盐诱导型激酶2（SIK2）抑制剂
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Application No.: US14101109Application Date: 2013-12-09
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Publication No.: US09260426B2Publication Date: 2016-02-16
- Inventor: Hariprasad Vankayalapati , Venkatakrishnareddy Yerramreddy , Venu Babu Ganipisetty , Sureshkumar Talluri , Rajendra P. Appalaneni
- Applicant: Arrien Pharmaceuticals LLC
- Applicant Address: US UT Salt Lake City
- Assignee: ARRIEN PHARMACEUTICALS LLC
- Current Assignee: ARRIEN PHARMACEUTICALS LLC
- Current Assignee Address: US UT Salt Lake City
- Agency: Gibson & Dernier LLP
- Agent Timothy X. Gibson, Esq.
- Main IPC: C07D471/04
- IPC: C07D471/04
![Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors](/abs-image/US/2016/02/16/US09260426B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds according to Formulas I, IA or IB: to pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.
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