An integrated circuit includes a programmable logic device and optionally a control circuit coupled to the programmable logic device (PLD). The control circuit may detect that a reconfiguration criterion is satisfied. Responsive to the reconfiguration criterion being satisfied, the control logic may configure, using one or more randomizations, the PLD to implement a secret operation, wherein a first randomized configuration of the PLD results in a first circuit implementation that is different from, but functionally equivalent to, a second circuit implementation that results from a second randomized configuration of the PLD.