The present invention relates to a network node and a method in method in a network node of a wireless communications system that allow for power efficient scheduling of transmission of application data over a radio interface. According to the method, information is received (71, 72) about a power consumption profile of a transmit unit and about estimated required average output transmission power of the transmit unit for transmitting an amount of application data in a time interval. The method also includes a step of making (73) a scheduling decision, comprising a type of load distribution to be used in the time interval for transmitting the amount of application data, based on the received information. In another step (74) the scheduling decision is provided to the transmit unit as a scheduling order for transmission of the application data over the radio interface. The invention also relates to a mobile station and core network node configured to provide a network node with power consumption profile information.