Invention Grant
- Patent Title: Local vascular delivery of probucol in combination with sirolimus
- Patent Title (中): 普罗布考联合西罗莫司的局部血管输送
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Application No.: US13972479Application Date: 2013-08-21
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Publication No.: US09265597B2Publication Date: 2016-02-23
- Inventor: Robert Falotico , Jonathon Z. Zhao
- Applicant: Wyeth LLC
- Assignee: Cordis Corporation; Wyeth LLC
- Current Assignee: Cordis Corporation; Wyeth LLC
- Agency: Dergosits & Noah LLP
- Main IPC: A61F2/06
- IPC: A61F2/06 ; A61F2/07 ; A61L31/10 ; A61L31/16

Abstract:
Medical devices, and in particular implantable medical devices, may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Public/Granted literature
Information query
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