Invention Grant
- Patent Title: Treatment of cardiovascular disease and thrombosis
- Patent Title (中): 治疗心血管疾病和血栓形成
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Application No.: US13363661Application Date: 2012-02-01
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Publication No.: US09265736B2Publication Date: 2016-02-23
- Inventor: Stanley Hazen , Zeneng Wang
- Applicant: Stanley Hazen , Zeneng Wang
- Applicant Address: US OH Cleveland
- Assignee: THE CLEVELAND CLINIC FOUNDATION
- Current Assignee: THE CLEVELAND CLINIC FOUNDATION
- Current Assignee Address: US OH Cleveland
- Agency: Casimir Jones, S.C.
- Agent Jason R. Bond
- Main IPC: A61K31/045
- IPC: A61K31/045 ; A61K31/43 ; A61K31/496 ; A61K31/14 ; A61K31/4164 ; A61K31/7048 ; A23L2/52 ; A23L1/30

Abstract:
Provided herein are compositions for the treatment and/or prevention of cardiovascular disease (CVD), and methods of application and use thereof. In particular, the present invention provides treatment and/or prevention of cardiovascular disease with 3,3-dimethyl-1-butanol (DMB) and related compounds, and pharmaceutical formulations thereof. In other embodiments, the present invention provides methods of administering a gut flora targeting antibiotic to a subject prior to a procedure that is associated with a risk of causing thrombosis, heart-attack, and/or platelet hyper-responsiveness.
Public/Granted literature
- US20120207822A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CARDIOVASCULAR DISEASE Public/Granted day:2012-08-16
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