In accordance with the present invention, there is provided a strainer system comprising a plurality of strainer modules, each of which comprises multiple cassettes or cartridges assembled together in a prescribed arrangement. In the strainer system constructed in accordance with the present invention, the “clean” sides of the strainer modules are fluidly connected to each other by a plenum duct which also has a suction pump fluidly coupled thereto. Integrated into the plenum duct is a pressure released membrane (PRM) which is positioned so as to effectively isolate one of the strainer modules from the remaining active strainer modules included in the strainer system. The pressure released membrane is uniquely configured so as to facilitate the activation of the isolated strainer module when pressure across the plenum duct increases beyond a prescribed threshold.