Invention Grant
- Patent Title: Inhibitors of Furin and other pro-protein convertases
- Patent Title (中): 弗林蛋白酶和其他亲蛋白转化酶的抑制剂
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Application No.: US14385714Application Date: 2013-03-14
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Publication No.: US09266828B2Publication Date: 2016-02-23
- Inventor: Alex Strongin , Maurizio Pellecchia , Elisa Barile
- Applicant: Sanford-Burnham Medical Research Institute
- Applicant Address: US CA La Jolla
- Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee Address: US CA La Jolla
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2013/031733 WO 20130314
- International Announcement: WO2013/138665 WO 20130919
- Main IPC: C07C279/04
- IPC: C07C279/04 ; A61K31/155 ; A61P35/00 ; C07C317/50 ; A61K38/00 ; C07K5/09 ; C07K5/062
Abstract:
Disclosed herein are Furin/PC inhibitors for inhibiting Furin and other Propprotein Convertases. Method of making the Furin/PC inhibitors, chemical and biological characterization of the Furin/PC inhibitors, and the use of the Furin/PC inhibitors to treat infectious diseases, cancers, and inflammatory/autoimmune disorders, are also disclosed.
Public/Granted literature
- US20150073054A1 INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES Public/Granted day:2015-03-12
Information query
