Invention Grant
- Patent Title: Quinoline derivatives useful as CB-1 inverse agonists
- Patent Title (中): 喹啉衍生物可用作CB-1反向激动剂
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Application No.: US14615560Application Date: 2015-02-06
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Publication No.: US09266835B2Publication Date: 2016-02-23
- Inventor: Bart DeCorte , Mark Macielag , Michael Greco , Yue-Mei Zhang , Christopher Teleha
- Applicant: JANSSEN PHARMACEUTICA NV
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Thomas J. Dodd
- Main IPC: C07D215/44
- IPC: C07D215/44 ; C07D417/14 ; C07D409/14 ; C07D417/06 ; C07D405/14 ; C07D401/12 ; C07D401/14 ; C07D409/06 ; C07D215/06 ; C07D215/42 ; C07D401/04
Abstract:
The present invention is directed to quinoline derivatives, pharmaceutical compositions containing said derivatives and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. For example, the compounds of the present invention are useful in the treatment of metabolic disorders.
Public/Granted literature
- US20150239844A1 QUINOLINE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS Public/Granted day:2015-08-27
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