Invention Grant
- Patent Title: Bicyclic AZA compounds as muscarinic M1 receptor agonists
- Patent Title (中): 双环AZA化合物作为毒蕈碱M1受体激动剂
-
Application No.: US14428927Application Date: 2013-09-18
-
Publication No.: US09266857B2Publication Date: 2016-02-23
- Inventor: Giles Albert Brown , Julie Elaine Cansfield , Miles Stuart Congreve , Mark Pickworth , Benjamin Gerald Tehan
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Hertfordshire
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Hertfordshire
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- International Application: PCT/GB2013/052442 WO 20130918
- International Announcement: WO2014/045031 WO 20140327
- Main IPC: C07D211/06
- IPC: C07D211/06 ; C07D295/00 ; C07D401/04
Abstract:
This invention relates to compounds (Formula (1)) that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where R1-R5, X1, X2 and p are as defined herein.
Public/Granted literature
- US20150232443A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS Public/Granted day:2015-08-20
Information query
