Invention Grant
- Patent Title: Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors
- Patent Title (中): 取代的吡唑并[3,4-d]嘧啶作为激酶抑制剂
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Application No.: US14374788Application Date: 2013-09-06
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Publication No.: US09266895B2Publication Date: 2016-02-23
- Inventor: Tim Owens , Erik Verner
- Applicant: PRINCIPIA BIOPHARMA INC.
- Applicant Address: US CA South San Francisco
- Assignee: Principia Biopharma Inc.
- Current Assignee: Principia Biopharma Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/US2013/058614 WO 20130906
- International Announcement: WO2014/039899 WO 20140313
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D239/70 ; C07D487/04 ; C07D519/00 ; A61K31/495 ; A61K31/506 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; A61K31/5377 ; A61K45/06
![Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors](/abs-image/US/2016/02/23/US09266895B2/abs.jpg.150x150.jpg)
Abstract:
The present disclosure provides compounds of Formula (IA) and or pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BTK, and are potentially useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer, inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and/or pharmaceutically acceptable salts thereof and processes for preparing such compounds and pharmaceutically acceptable salts thereof.
Public/Granted literature
- US20150094295A1 PYRAZOLOPYRIMIDINE COMPOUNDS AS KINASE INHIBITORS Public/Granted day:2015-04-02
Information query
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