Invention Grant
- Patent Title: Inhibitors of arginase and their therapeutic applications
- Patent Title (中): 精氨酸酶抑制剂及其治疗应用
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Application No.: US14352554Application Date: 2012-10-18
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Publication No.: US09266908B2Publication Date: 2016-02-23
- Inventor: Michael Van Zandt , Adam Golebiowski , Min Koo Ji , Darren Whitehouse , Todd Ryder , Raymond Paul Beckett
- Applicant: MARS, INCORPORATED
- Applicant Address: US VA McLean
- Assignee: MARS, INCORPORATED
- Current Assignee: MARS, INCORPORATED
- Current Assignee Address: US VA McLean
- Agency: Foley Hoag LLP
- Agent David P. Halstead
- International Application: PCT/US2012/060789 WO 20121018
- International Announcement: WO2013/059437 WO 20130425
- Main IPC: C07F5/02
- IPC: C07F5/02
Abstract:
The inventive compounds are small molecule therapeutics that are potent inhibitors of Arginase I and II activity. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the inventive compounds for treating or preventing a disease or a condition associated with arginase activity.
Public/Granted literature
- US20140343019A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS Public/Granted day:2014-11-20
Information query
