Invention Grant
- Patent Title: Modified vitamin K-dependent polypeptides
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Application No.: US14100390Application Date: 2013-12-09
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Publication No.: US09266931B2Publication Date: 2016-02-23
- Inventor: Gary L. Nelsestuen
- Applicant: Regents of the University of Minnesota
- Applicant Address: US MN Minneapolis
- Assignee: Regents of the University of Minnesota
- Current Assignee: Regents of the University of Minnesota
- Current Assignee Address: US MN Minneapolis
- Agency: Fish & Richardson P.C.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K38/36 ; A61K38/16 ; C07K14/47 ; A61K38/48 ; C07K14/745 ; C12N9/64 ; A61K45/00 ; C07K14/00
Abstract:
The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.
Public/Granted literature
- US20140113330A1 MODIFIED VITAMIN K-DEPENDENT POLYPEPTIDES Public/Granted day:2014-04-24
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