Invention Grant
US09267114B2 Flavivirus envelope protein mutations affecting virion disassembly
有权
影响病毒粒子分解的黄病毒包膜蛋白突变
- Patent Title: Flavivirus envelope protein mutations affecting virion disassembly
- Patent Title (中): 影响病毒粒子分解的黄病毒包膜蛋白突变
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Application No.: US13671111Application Date: 2012-11-07
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Publication No.: US09267114B2Publication Date: 2016-02-23
- Inventor: Vladimir Yamshchikov
- Applicant: Southern Research Institute
- Applicant Address: US AL Birmingham
- Assignee: SOUTHERN RESEARCH INSTITUTE
- Current Assignee: SOUTHERN RESEARCH INSTITUTE
- Current Assignee Address: US AL Birmingham
- Agency: Stinson Leonard Street LLP
- Main IPC: C12N7/04
- IPC: C12N7/04 ; C07K14/005 ; A61K39/12 ; C12N7/00 ; A61K39/00
Abstract:
Mutations in the central monomer contact interface of the flavivirus envelope protein which modulate the infectivity of the flavivirus are made. The mutations decrease the ability of the envelope dimer protein to dissociate.
Public/Granted literature
- US20140127261A1 Flavivirus Envelope Protein Mutations Affecting Virion Disassembly Public/Granted day:2014-05-08
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