Invention Grant
- Patent Title: Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene
- Patent Title (中): 通过抑制胰腺发育基因的天然反义转录物治疗胰腺发育基因相关疾病
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Application No.: US14534323Application Date: 2014-11-06
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Publication No.: US09267136B2Publication Date: 2016-02-23
- Inventor: Joseph Collard , Olga Khorkova Sherman
- Applicant: CuRNA, Inc.
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/113 ; A61K31/7088 ; C12Q1/68
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Pancreatic Developmental gene, in particular, by targeting natural antisense polynucleotides of a Pancreatic Developmental gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Pancreatic Developmental genes.
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