A light-emitting diode bulb with loudspeaker function includes a bulb head, a drive power assembly, a heat radiator, a light-emitting diode module, a loudspeaker assembly, and a cover covered on the heat radiator. The drive power assembly is assembled to an upper portion of the bulb head, and is electrically connected with the bulb head. The drive power assembly includes a power supply circuit board assembly and a wireless module. The heat radiator is mounted to the upper portion of the bulb head. The drive power assembly is received in the heat radiator. The light-emitting diode module is mounted on the heat radiator, and is electrically connected with the power supply circuit board assembly. The loudspeaker assembly mounted on the light-emitting diode module, the heat radiator and the drive power assembly includes a fastening holder, an audio circuit board, a fastening bracket and a speaker unit.