A manifold for a liquid dispensing system has at least two layers. The first layer has multiple through holes along its thickness direction, and one or more fluid channels perpendicular to the thickness direction. The second layer has one or more through holes along its thickness direction, each communicating with one of the through holes of the first layer. The second layer also has one or more fluid channels perpendicular to the thickness direction. The fluid channels each have an inlet at the edge of the respective layer and an outlet at one of the through holes. The second layer also has one or more holes defining valve bores. A valve in each of the valve bores controls flow of a liquid to a respective one of the fluid channels of the second layer. Also provided are a liquid dispensing system and a method of manufacturing a manifold.