Invention Grant
US09271944B2 Ketoprofen-containing aqueous adhesive skin patch 有权
含酮洛芬的水性胶粘剂皮肤贴片

  • Patent Title: Ketoprofen-containing aqueous adhesive skin patch
  • Patent Title (中): 含酮洛芬的水性胶粘剂皮肤贴片
  • Application No.: US13583940
    Application Date: 2011-03-11
  • Publication No.: US09271944B2
    Publication Date: 2016-03-01
  • Inventor: Kazuha Tani
  • Applicant: Kazuha Tani
  • Applicant Address: JP Higashikagawa-shi
  • Assignee: Teikoku Seiyaku Co., Ltd.
  • Current Assignee: Teikoku Seiyaku Co., Ltd.
  • Current Assignee Address: JP Higashikagawa-shi
  • Agency: Crowell & Moring LLP
  • Priority: JP2010-056098 20100312
  • International Application: PCT/JP2011/055728 WO 20110311
  • International Announcement: WO2011/111809 WO 20110915
  • Main IPC: A61K9/70
  • IPC: A61K9/70 A61K31/192 A61K47/10
Ketoprofen-containing aqueous adhesive skin patch
Abstract:
Provided is a water-based patch that contains ketoprofen as an active ingredient, provides high transdermal absorbability of the ketoprofen, and has high safety and high storage stability. The water-based patch contains the ketoprofen, an amine, and polyethylene glycol. In the water-based patch, the added amount of the ketoprofen in a paste is 0.1 to 5% by weight, the added amount of the amine in the paste is 0.5 to 10% by weight, and the added amount of the polyethylene glycol in the paste is 5 to 30% by weight. Particularly, in the water-based patch, diisopropanolamine is used as the amine.
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