Invention Grant
- Patent Title: Ketoprofen-containing aqueous adhesive skin patch
- Patent Title (中): 含酮洛芬的水性胶粘剂皮肤贴片
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Application No.: US13583940Application Date: 2011-03-11
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Publication No.: US09271944B2Publication Date: 2016-03-01
- Inventor: Kazuha Tani
- Applicant: Kazuha Tani
- Applicant Address: JP Higashikagawa-shi
- Assignee: Teikoku Seiyaku Co., Ltd.
- Current Assignee: Teikoku Seiyaku Co., Ltd.
- Current Assignee Address: JP Higashikagawa-shi
- Agency: Crowell & Moring LLP
- Priority: JP2010-056098 20100312
- International Application: PCT/JP2011/055728 WO 20110311
- International Announcement: WO2011/111809 WO 20110915
- Main IPC: A61K9/70
- IPC: A61K9/70 ; A61K31/192 ; A61K47/10

Abstract:
Provided is a water-based patch that contains ketoprofen as an active ingredient, provides high transdermal absorbability of the ketoprofen, and has high safety and high storage stability. The water-based patch contains the ketoprofen, an amine, and polyethylene glycol. In the water-based patch, the added amount of the ketoprofen in a paste is 0.1 to 5% by weight, the added amount of the amine in the paste is 0.5 to 10% by weight, and the added amount of the polyethylene glycol in the paste is 5 to 30% by weight. Particularly, in the water-based patch, diisopropanolamine is used as the amine.
Public/Granted literature
- US20130005817A1 Ketoprofen-Containing Aqueous Adhesive Skin Patch Public/Granted day:2013-01-03
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