Invention Grant
US09271962B2 Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors
有权
脂肪酸酰胺水解酶和单酰基甘油脂肪酶抑制剂用于调节大麻素受体
- Patent Title: Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase for modulation of cannabinoid receptors
- Patent Title (中): 脂肪酸酰胺水解酶和单酰基甘油脂肪酶抑制剂用于调节大麻素受体
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Application No.: US12933322Application Date: 2009-03-17
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Publication No.: US09271962B2Publication Date: 2016-03-01
- Inventor: Alexandros Makriyannis , Lakshmipathi Pandarinathan , Nikolai Zvonok , Teija Parkkari , Lauren Chapman
- Applicant: Alexandros Makriyannis , Lakshmipathi Pandarinathan , Nikolai Zvonok , Teija Parkkari , Lauren Chapman
- Applicant Address: US MA Boston
- Assignee: NORTHEASTERN UNIVERSITY
- Current Assignee: NORTHEASTERN UNIVERSITY
- Current Assignee Address: US MA Boston
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- International Application: PCT/US2009/037434 WO 20090317
- International Announcement: WO2009/117444 WO 20090924
- Main IPC: C07D233/90
- IPC: C07D233/90 ; A61K31/41 ; A61K31/415 ; C07D231/12 ; C07D233/56 ; C07D235/08 ; C07D249/08 ; C07D249/18 ; C07D263/22 ; C07D401/12 ; C07D471/04 ; C07D473/00 ; C07D473/28 ; G01N21/64
Abstract:
Disclosed are compounds and compositions that inhibit the action of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL), methods of inhibiting FAAH and MGL, methods of modulating cannabinoid receptors, and methods of treating various disorders related to modulation of cannabinoid receptors.
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