Invention Grant
US09271970B2 Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase
有权
萘啶衍生物作为缺氧诱导因子（HIF）羟化酶的抑制剂
- Patent Title: Naphthyridine derivatives as inhibitors of hypoxia inducible factor (HIF) hydroxylase
- Patent Title (中): 萘啶衍生物作为缺氧诱导因子（HIF）羟化酶的抑制剂
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Application No.: US14581592Application Date: 2014-12-23
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Publication No.: US09271970B2Publication Date: 2016-03-01
- Inventor: Danny Ng , Michael P. Arend , Lee A. Flippin
- Applicant: FibroGen, Inc.
- Applicant Address: US CA San Francisco
- Assignee: FIBROGEN, INC.
- Current Assignee: FIBROGEN, INC.
- Current Assignee Address: US CA San Francisco
- Agency: Sheppard Mullin Richter & Hampton LLP
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4375 ; A61K31/444 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; A61K45/06
Abstract:
The present disclosure relates to novel compounds, methods, and compositions capable of inhibiting HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
Public/Granted literature
- US20150174110A1 NAPHTHYRIDINE DERIVATIVES AS INHIBITORS OF HYPOXIA INDUCIBLE FACTOR (HIF) HYDROXYLASE Public/Granted day:2015-06-25
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