Invention Grant
- Patent Title: AAV-based treatment of cholesterol-related disorders
- Patent Title (中): 基于AAV的胆固醇相关疾病的治疗
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Application No.: US13642740Application Date: 2011-04-22
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Publication No.: US09272053B2Publication Date: 2016-03-01
- Inventor: Guangping Gao , Phillip D. Zamore , Jun Xie
- Applicant: Guangping Gao , Phillip D. Zamore , Jun Xie
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2011/033628 WO 20110422
- International Announcement: WO2011/133901 WO 20111027
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K48/00 ; C12Q1/68 ; C12N15/86
Abstract:
The invention in some aspects relates to methods and compositions for assessing the effectiveness of miRNA inhibitors. In other aspects of the invention, methods and compositions for treating cholesterol related disorders are provided. In one aspect of the invention, miRNA inhibitors against miR-122 and rAAV-based compositions comprising the same are provided.
Public/Granted literature
- US20130101558A1 AAV-BASED TREATMENT OF CHOLESTEROL-RELATED DISORDERS Public/Granted day:2013-04-25
Information query
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