Invention Grant
US09272261B2 Organic-inorganic hybrid chiral sorbent and process for the preparation thereof 有权
有机 - 无机杂化手性吸附剂及其制备方法

Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
Abstract:
The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2-phenyl propionic acid, diethyl tartrate, 2,2′-dihydroxy-1,1′-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral separation (enantiomeric excess, 99%) in case of mandelic acid under medium pressure column chromatography. These optically pure enantiomers find applications as intermediates in pharmaceutical industries.
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