Invention Grant
US09272992B2 (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-l-carboxylic acid hydrates pharmaceutical uses thereof
有权
（1S，2S，3S，4R）-3 - [（1S）-1-乙酰氨基-2-乙基 - 丁基] -4-胍基-2-羟基 - 环戊基-1-羧酸水合物
![(1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-l-carboxylic acid hydrates pharmaceutical uses thereof](/docs/US/2016-03-01/US09272992B2/abs.jpg.600x600.jpg)
- Patent Title: (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-l-carboxylic acid hydrates pharmaceutical uses thereof
- Patent Title (中): （1S，2S，3S，4R）-3 - [（1S）-1-乙酰氨基-2-乙基 - 丁基] -4-胍基-2-羟基 - 环戊基-1-羧酸水合物
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Application No.: US13968645Application Date: 2013-08-16
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Publication No.: US09272992B2Publication Date: 2016-03-01
- Inventor: Song Li , Wu Zhong , Zhibing Zheng , Xinbo Zhou , Junhai Xiao , Yunde Xie , Lili Wang , Xingzhou Li , Guoming Zhao , Xiaokui Wang , Hongying Liu
- Applicant: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China
- Applicant Address: CN Beijing
- Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China
- Current Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China
- Current Assignee Address: CN Beijing
- Agency: Brinks Gilson & Lione
- Priority: CN200710143607 20070814
- Main IPC: A61K31/24
- IPC: A61K31/24 ; A01N37/12 ; A01N37/44 ; C07C279/16 ; C07C277/06 ; C07C277/08
![(1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-l-carboxylic acid hydrates pharmaceutical uses thereof](/abs-image/US/2016/03/01/US09272992B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to (1S,2S,3S,4R)-3-[(1S)-1-acetylamino-2-ethyl-butyl]-4-guanidino-2-hydroxy-cyclopentyl-1-carboxylic acid hydrates compounds, preparing methods thereof, pharmaceutical compositions containing said compounds and preparing methods thereof, and the clinical uses of said compounds as neuramidinase inhibitors for anti-influenza.
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