Invention Grant
- Patent Title: Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof
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Application No.: US14520098Application Date: 2014-10-21
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Publication No.: US09273025B2Publication Date: 2016-03-01
- Inventor: Daria Mochly-Rosen , Che-Hong Chen , Xiaohu Ouyang
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees—Leland Stanford Junior University
- Current Assignee: The Board of Trustees—Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Rudy J. Ng; Paula A. Borden
- Main IPC: A61K31/36
- IPC: A61K31/36 ; C07D317/58 ; C07D405/12
Abstract:
The present invention provides compounds that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. The present invention further provides assays for identifying agonists of ALDH2.
Public/Granted literature
- US09315484B2 Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof Public/Granted day:2016-04-19
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