Invention Grant
- Patent Title: Pyridine-and pyrazine derivatives
- Patent Title (中): 吡啶和吡嗪衍生物
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Application No.: US14118845Application Date: 2012-04-11
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Publication No.: US09273029B2Publication Date: 2016-03-01
- Inventor: Guenter Hoelzemann , Hans-Michael Eggenweiler , Srinivasa R. Karra
- Applicant: Guenter Hoelzemann , Hans-Michael Eggenweiler , Srinivasa R. Karra
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: EMD Serono Research Institute
- Agent Thomas W. Brown
- International Application: PCT/US2012/032983 WO 20120411
- International Announcement: WO2012/161877 WO 20121129
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/444 ; A61K31/4545 ; A61K31/496 ; A61K31/497 ; A61K31/501 ; A61K31/5377 ; A61K45/06 ; C07D401/14 ; C07D405/14 ; C07D409/14 ; C07D471/04 ; C07D491/048 ; C07D409/04
Abstract:
Compounds of the formula (I) in which R, R1 and X have the meanings indicated in claim 1, are inhibitors of TBK1 and IKKε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases
Public/Granted literature
- US20140142097A1 PYRIDINE-AND PYRAZINE DERIVATIVES Public/Granted day:2014-05-22
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