Invention Grant
- Patent Title: Moenomycin analogs, methods of synthesis, and uses thereof
- Patent Title (中): 霉酚霉素类似物，合成方法及其用途
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Application No.: US14390811Application Date: 2013-04-05
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Publication No.: US09273084B2Publication Date: 2016-03-01
- Inventor: Daniel Evan Kahne , Suzanne Walker Kahne , Hirokazu Tsukamoto
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2013/035416 WO 20130405
- International Announcement: WO2013/152277 WO 20131010
- Main IPC: C07H5/06
- IPC: C07H5/06 ; C07H13/12 ; C07F9/6558
Abstract:
The present invention provides compounds of Formula (I); or a pharmaceutically acceptable form thereof; wherein R1,R2,R3,R6,R7,R12,Ra, and Rb are as defined herein, and G is a group of Formula (a), (b), or (c): Formula (II), wherein X1; X2, X3, X4, X5, X6, X7, Y, RC, Rd, Rz, a, d, e, x, n, and m are as defined herein. The present invention further provides pharmaceutical compositions comprising a compound of Formula (I), kits comprising such compositions, methods of use and treatment, and preparative methods.
Public/Granted literature
- US20150119354A1 MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF Public/Granted day:2015-04-30
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