Invention Grant
- Patent Title: α4β7 peptide dimer antagonists
- Patent Title (中): α4＆bgr。7肽二聚体拮抗剂
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Application No.: US14050349Application Date: 2013-10-10
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Publication No.: US09273093B2Publication Date: 2016-03-01
- Inventor: Ashok Bhandari , Dinesh V. Patel , Larry C. Mattheakis
- Applicant: Protagonist Therapeutics, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Protagonist Therapeutics, Inc.
- Current Assignee: Protagonist Therapeutics, Inc.
- Current Assignee Address: US CA Menlo Park
- Agency: Cooley LLP
- Main IPC: C07K7/06
- IPC: C07K7/06 ; C07K7/08 ; C07K14/47 ; A61K38/00
Abstract:
The invention relates to disulfide-rich dimer molecules which inhibit binding of α4β7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, and show high selectivity against α4β1 binding.
Public/Granted literature
- US20140193465A1 NOVEL a4B7 PEPTIDE DIMER ANTAGONISTS Public/Granted day:2014-07-10
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