Production of glycoproteins using manganese

Invention Grant

US09273110B2 Production of glycoproteins using manganese 有权

Patent Title: Production of glycoproteins using manganese
Application No.: US14087747

Application Date: 2013-11-22
Publication No.: US09273110B2

Publication Date: 2016-03-01
Inventor: Christopher Kenyon Crowell , Gustavo Enrique Grampp
Applicant: AMGEN INC.
Applicant Address: US CA Thousand Oaks
Assignee: Amgen Inc.
Current Assignee: Amgen Inc.
Current Assignee Address: US CA Thousand Oaks
Agent Petrina S. Hsi
Main IPC: C12N15/09
IPC: C12N15/09 ; C12N15/16 ; C12N1/00 ; C07K14/505 ; C07K14/575 ; C12N5/00 ; C12P21/00

Abstract:

Culture media comprising manganese and methods of culturing cells to improve sialylation and glycosylation of glycoproteins are provided.

Public/Granted literature

Information query

Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术