A solid-state image sensor including an effective pixel area in which a plurality of pixels are two-dimensionally arranged, each of the plurality of pixels comprising a photoelectric conversion portion configured to generate charges by photoelectric conversion, a charge holding portion configured to hold the charges generated by the photoelectric conversion portion, a floating diffusion portion configured to convert the charges from the charge holding portion into a voltage, a first transfer portion configured to transfer the charges of the photoelectric conversion portion to the charge holding portion, and a second transfer portion configured to transfer the charges of the charge holding portion to the floating diffusion portion, wherein the charge holding portion of each of the plurality of pixels is arranged on the inner side of the photoelectric conversion portion with respect to the center of the effective pixel area.