A method of wireless communication includes monitoring coexistence issues among supported radios in a User Equipment (UE). The method includes determining a coexistence policy for communication resource operation within a user equipment (UE) and configuring communication resources of the user equipment in accordance with the determined coexistence policy. The policy may give priority to an LTE modem, an ISM modem, or may implement a variable priority scheme. The policy may be communicated to each modem from a host over a software messaging communication line. Modems in the UE may communicate with each other through logical lines providing real time communication. The policy may determine the operation of each modem and the treatment of the logical lines by each modem.