Invention Grant
- Patent Title: Press-coated orally-disintegrating tablets
- Patent Title (中): 压片包衣口腔崩解片
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Application No.: US13513956Application Date: 2010-12-10
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Publication No.: US09278063B2Publication Date: 2016-03-08
- Inventor: Yuki Ikeda , Yasushi Ochiai
- Applicant: Yuki Ikeda , Yasushi Ochiai
- Applicant Address: JP Osaka
- Assignee: SUMITOMO DAINIPPON PHARMA CO., LTD.
- Current Assignee: SUMITOMO DAINIPPON PHARMA CO., LTD.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2009-281216 20091211
- International Application: PCT/JP2010/072203 WO 20101210
- International Announcement: WO2011/071139 WO 20110616
- Main IPC: A61K9/36
- IPC: A61K9/36 ; A61K9/00 ; A61K9/28

Abstract:
The purpose of the invention is to provide a press-coated orally-disintegrating tablet having a powder/granular material with poor formability in its inner core, which has an excellent disintegrability and a suitable hardness as a whole tablet. Furthermore, the invention is a press-coated orally-disintegrating tablet with an outer layer surrounding an inner core wherein the inner core has a thickness in the range of 30 to 80% per that of the whole tablet, and the outer layer comprises (a) microcrystalline cellulose, (b) a sugar or a sugar alcohol, and (c) one or more particular ingredients selected from the group consisting of crospovidone, starches, low-substituted hydroxypropylcellulose and carmellose.
Public/Granted literature
- US20120237602A1 PRESS-COATED ORALLY-DISINTEGRATING TABLETS Public/Granted day:2012-09-20
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