Invention Grant
- Patent Title: Delivery systems for solubilising water-insoluble pharmaceutical active ingredients
- Patent Title (中): 用于增溶水不溶性药物活性成分的递送系统
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Application No.: US12672574Application Date: 2008-08-11
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Publication No.: US09278065B2Publication Date: 2016-03-08
- Inventor: Flavia Giuliana Tinti , Marcia Cristina Breitkreitz , Vladimir Matha , Carlo Oliani
- Applicant: Flavia Giuliana Tinti , Marcia Cristina Breitkreitz , Carlo Oliani
- Applicant Address: BR HORTOLANDIA
- Assignee: EMS S/A
- Current Assignee: EMS S/A
- Current Assignee Address: BR HORTOLANDIA
- Agency: The Dobrusin Law Firm, P.C.
- Priority: GB0715493.3 20070809
- International Application: PCT/IB2008/002552 WO 20080811
- International Announcement: WO2009/019604 WO 20090212
- Main IPC: A61K9/107
- IPC: A61K9/107 ; A61K9/48 ; A61K31/07
Abstract:
A delivery system for water-insoluble pharmaceutical active ingredients is provided. The delivery system includes water-insoluble pharmaceutical active ingredient(s), organic solvent(s) and amphiphilic co-solvent(s), and a mixture of hydrophilic and hydrophobic non-ionic surfactants. Upon dilution in an aqueous medium, this formulation forms spontaneously dispersion of non-ionic surfactant nanoparticles.
Public/Granted literature
- US20120177692A1 DELIVERY SYSTEMS FOR SOLUBILISING WATER-INSOLUBLE PHARMACEUTICAL ACTIVE INGREDIENTS Public/Granted day:2012-07-12
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